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Lipid Droplet-Binding Protein TIP47 Regulates Hepatitis C Virus RNA Replication through Interaction with the Viral NS5A Protein
The nonstructural protein NS5A has emerged as a new drug target in antiviral therapies for Hepatitis C Virus (HCV) infection. NS5A is critically involved in viral RNA replication that takes place at newly formed membranes within the endoplasmic reticulum (membranous web) and assists viral assembly i...
Autores principales: | Vogt, Dorothee A., Camus, Grégory, Herker, Eva, Webster, Brian R., Tsou, Chia-Lin, Greene, Warner C., Yen, Tien-Sze Benedict, Ott, Melanie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623766/ https://www.ncbi.nlm.nih.gov/pubmed/23593007 http://dx.doi.org/10.1371/journal.ppat.1003302 |
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