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Lymphoma B-cell responsiveness to CpG-DNA depends on the tumor microenvironment

BACKGROUND: Toll-like receptor (TLR) agonists have important properties that can be exploited for immunotherapy against tumors. Locally injected immunostimulatory oligodeoxynucleotides containing CpG motifs (CpG-ODNs), which are TLR9 agonists, have shown promise in cancer models. Several studies hav...

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Detalles Bibliográficos
Autores principales: Ben Abdelwahed, Rym, Cosette, Jérémie, Donnou, Sabrina, Crozet, Lucile, Ouakrim, Hanane, Fridman, Wolf Herman, Sautès-Fridman, Catherine, Mahjoub, Aouni, Fisson, Sylvain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623776/
https://www.ncbi.nlm.nih.gov/pubmed/23561041
http://dx.doi.org/10.1186/1756-9966-32-18

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