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Alcohol ingestion disrupts alveolar epithelial barrier function by activation of macrophage-derived transforming growth factor beta1

BACKGROUND: Chronic alcohol abuse causes oxidative stress and impairs alveolar epithelial barrier integrity, thereby rendering the lung susceptible to acute edematous injury. Experimentally, alcohol-induced oxidative stress increases the expression of transforming growth factor β1 (TGFβ1) in the lun...

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Detalles Bibliográficos
Autores principales: Curry-McCoy, Tiana V, Venado, Aida, Guidot, David M, Joshi, Pratibha C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623812/
https://www.ncbi.nlm.nih.gov/pubmed/23547562
http://dx.doi.org/10.1186/1465-9921-14-39

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