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Alcohol ingestion disrupts alveolar epithelial barrier function by activation of macrophage-derived transforming growth factor beta1
BACKGROUND: Chronic alcohol abuse causes oxidative stress and impairs alveolar epithelial barrier integrity, thereby rendering the lung susceptible to acute edematous injury. Experimentally, alcohol-induced oxidative stress increases the expression of transforming growth factor β1 (TGFβ1) in the lun...
Autores principales: | Curry-McCoy, Tiana V, Venado, Aida, Guidot, David M, Joshi, Pratibha C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623812/ https://www.ncbi.nlm.nih.gov/pubmed/23547562 http://dx.doi.org/10.1186/1465-9921-14-39 |
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