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Mutational spectrum of the APC and MUTYH genes and genotype–phenotype correlations in Brazilian FAP, AFAP, and MAP patients

BACKGROUND: Patients with multiple colorectal adenomas are currently screened for germline mutations in two genes, APC and MUTYH. APC-mutated patients present classic or attenuated familial adenomatous polyposis (FAP/AFAP), while patients carrying biallelic MUTYH mutations exhibit MUTYH-associated p...

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Detalles Bibliográficos
Autores principales:	Torrezan, Giovana Tardin, da Silva, Felipe Cavalcanti Carneiro, Santos, Érika Maria Monteiro, Krepischi, Ana Cristina Victorino, Achatz, Maria Isabel Waddington, Junior, Samuel Aguiar, Rossi, Benedito Mauro, Carraro, Dirce Maria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623842/ https://www.ncbi.nlm.nih.gov/pubmed/23561487 http://dx.doi.org/10.1186/1750-1172-8-54

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