Cargando…

Shedding LIGHT (TNFSF14) on the tumor microenvironment of colorectal cancer liver metastases

BACKGROUND: T-cell infiltration in primary colon tumors is associated with improved patient survival. Preliminary data supports a similar association in colorectal liver metastases (CRLM), and we previously identified increased CRLM expression of the immunostimulatory cytokine LIGHT (TNFSF14) to be...

Descripción completa

Detalles Bibliográficos
Autores principales:	Qin, Jian Zhong, Upadhyay, Vivek, Prabhakar, Bellur, Maker, Ajay V
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623860/ https://www.ncbi.nlm.nih.gov/pubmed/23514280 http://dx.doi.org/10.1186/1479-5876-11-70

Ejemplares similares

TNFSF14: LIGHTing the Way for Effective Cancer Immunotherapy
por: Skeate, Joseph G., et al.
Publicado: (2020)

The Potential of Intralesional Rose Bengal to Stimulate T-Cell Mediated Anti-Tumor Responses
por: Maker, Ajay V, et al.
Publicado: (2015)

High levels of LIGHT/TNFSF14 in patients with Prader–Willi syndrome
por: Faienza, M. F., et al.
Publicado: (2023)

Dissecting Abdominal Aortic Aneurysm Is Aggravated by Genetic Inactivation of LIGHT (TNFSF14)
por: Herrero-Cervera, Andrea, et al.
Publicado: (2021)

Comprehensive characterization of TNFSF14/LIGHT with implications in prognosis and immunotherapy of human gliomas
por: Han, Mingzhi, et al.
Publicado: (2022)

Increased Serum Levels of LIGHT/TNFSF14 in Nonalcoholic Fatty Liver Disease: Possible Role in Hepatic Inflammation
por: Otterdal, Kari, et al.
Publicado: (2015)

LIGHT/TNFSF14 increases osteoclastogenesis and decreases osteoblastogenesis in multiple myeloma-bone disease
por: Brunetti, Giacomina, et al.
Publicado: (2014)

Identification of a Novel OX40L(+) Dendritic Cell Subset That Selectively Expands Regulatory T cells
por: Marinelarena, Alejandra, et al.
Publicado: (2018)

Plasma TNFSF13B and TNFSF14 Function as Inflammatory Indicators of Severe Adenovirus Pneumonia in Pediatric Patients
por: Fan, Huifeng, et al.
Publicado: (2021)

Targeting the metabolic pathway of human colon cancer overcomes resistance to TRAIL-induced apoptosis
por: Carr, Ryan M, et al.
Publicado: (2016)

LIGHT (TNFSF14) enhances osteogenesis of human bone marrow-derived mesenchymal stem cells
por: Heo, Sook-Kyoung, et al.
Publicado: (2021)

Circulating LIGHT (TNFSF14) and Interleukin-18 Levels in Sepsis-Induced Multi-Organ Injuries
por: Qu, Hui-Qi, et al.
Publicado: (2022)

Therapeutic advances in anaplastic thyroid cancer: a current perspective
por: Saini, Shikha, et al.
Publicado: (2018)

Mitochondrial protein 18 (MTP18) plays a pro-apoptotic role in chemotherapy-induced gastric cancer cell apoptosis
por: Aung, Lynn H.H., et al.
Publicado: (2017)

LIGHT (TNFSF14) Increases the Survival and Proliferation of Human Bone Marrow-Derived Mesenchymal Stem Cells
por: Heo, Sook-Kyoung, et al.
Publicado: (2016)

TNFSF14 (LIGHT) Exhibits Inflammatory Activities in Lung Fibroblasts Complementary to IL-13 and TGF-β
por: da Silva Antunes, Ricardo, et al.
Publicado: (2018)

TNFSF14/LIGHT, a Non-Canonical NF-κB Stimulus, Induces the HIF Pathway
por: D’Ignazio, Laura, et al.
Publicado: (2018)

Circulating soluble LIGHT/TNFSF14 is increased and associated with IL-8 concentration in chronic spontaneous urticaria
por: Kasperska-Zając, Alicja, et al.
Publicado: (2018)

Colon cancer cell treatment with rose bengal generates a protective immune response via immunogenic cell death
por: Qin, Jianzhong, et al.
Publicado: (2017)

Associations between TNFSF4, TNFSF8 and TNFSF15 and Behçet's disease but not VKH syndrome in Han Chinese
por: Jiang, Yan, et al.
Publicado: (2017)

LIGHT/TNFSF14 as a New Biomarker of Bone Disease in Multiple Myeloma Patients Experiencing Therapeutic Regimens
por: Brunetti, Giacomina, et al.
Publicado: (2018)

Molecular and Clinical Characterization of LIGHT/TNFSF14 Expression at Transcriptional Level via 998 Samples With Brain Glioma
por: Yang, Ying, et al.
Publicado: (2021)

Two Functionally Distinct Isoforms of TL1A (TNFSF15) Generated by Differential Ectodomain Shedding
por: Mück, Christoph, et al.
Publicado: (2010)

Shedding Light on the Role of Neurotransmitters in the Microenvironment of Pancreatic Cancer
por: Liang, Yiyi, et al.
Publicado: (2021)

Evolution of tumor microenvironment in colorectal liver metastases under treatment stress
por: Huang, Na, et al.
Publicado: (2022)

Effect of Tumor Necrosis Factor Family Member LIGHT (TNFSF14) on the Activation of Basophils and Eosinophils Interacting with Bronchial Epithelial Cells
por: Qiu, Huai Na, et al.
Publicado: (2014)

LIGHT (TNFSF14) promotes the differentiation of human bone marrow-derived mesenchymal stem cells into functional hepatocyte-like cells
por: Heo, Sook-Kyoung, et al.
Publicado: (2023)

Loss of MADD expression inhibits cellular growth and metastasis in anaplastic thyroid cancer
por: Saini, Shikha, et al.
Publicado: (2019)

LIGHT enhanced bispecific antibody armed T-cells to treat immunotherapy resistant colon cancer
por: Qiao, Guilin, et al.
Publicado: (2022)

TNFSF14-Derived Molecules as a Novel Treatment for Obesity and Type 2 Diabetes
por: Agostino, Mark, et al.
Publicado: (2021)

Age-Dependent Association of TNFSF15/TNFSF8 Variants and Leprosy Type 1 Reaction
por: Fava, Vinicius M., et al.
Publicado: (2017)

LIGHT/TNFSF14 is increased in patients with type 2 diabetes mellitus and promotes islet cell dysfunction and endothelial cell inflammation in vitro
por: Halvorsen, Bente, et al.
Publicado: (2016)

The Tumor Necrosis Factor Superfamily Members TNFSF14 (LIGHT), Lymphotoxin β and Lymphotoxin β Receptor Interact to Regulate Intestinal Inflammation
por: Giles, Daniel A., et al.
Publicado: (2018)

Combination of LIGHT (TNFSF14)-Armed Myxoma Virus Pre-Loaded into ADSCs and Gemcitabine in the Treatment of Experimental Orthotopic Murine Pancreatic Adenocarcinoma
por: Jazowiecka-Rakus, Joanna, et al.
Publicado: (2022)

TNFSF15 Promotes Antimicrobial Pathways in Human Macrophages and These Are Modulated by TNFSF15 Disease-Risk Variants
por: Sun, Rui, et al.
Publicado: (2020)

Myxoma Virus Expressing LIGHT (TNFSF14) Pre-Loaded into Adipose-Derived Mesenchymal Stem Cells Is Effective Treatment for Murine Pancreatic Adenocarcinoma
por: Jazowiecka-Rakus, Joanna, et al.
Publicado: (2021)

Multi-perspective comparison of the immune microenvironment of primary colorectal cancer and liver metastases
por: He, Yangsong, et al.
Publicado: (2022)

Myocyte-derived Tnfsf14 is a survival factor necessary for myoblast differentiation and skeletal muscle regeneration
por: Waldemer-Streyer, R J, et al.
Publicado: (2015)

Identification of immunologic subtype and prognosis of GBM based on TNFSF14 and immune checkpoint gene expression profiling
por: Long, Shengrong, et al.
Publicado: (2020)

PKC-ѳ is dispensable for OX40L-induced TCR-independent Treg proliferation but contributes by enabling IL-2 production from effector T-cells
por: Alharshawi, Khaled, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_r9spfn5igrlpc319gved099382