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Polymyxins as Novel and Safe Mucosal Adjuvants to Induce Humoral Immune Responses in Mice
There is currently an urgent need to develop safe and effective adjuvants for enhancing vaccine-induced antigen-specific immune responses. We demonstrate here that intranasal immunization with clinically used polypeptide antibiotics, polymyxin B (PMB) and colistin (CL), along with ovalbumin (OVA), i...
Autores principales: | Yoshino, Naoto, Endo, Masahiro, Kanno, Hiroyuki, Matsukawa, Naomi, Tsutsumi, Reiko, Takeshita, Ryosuke, Sato, Shigehiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623863/ https://www.ncbi.nlm.nih.gov/pubmed/23593492 http://dx.doi.org/10.1371/journal.pone.0061643 |
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