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Polymyxins as Novel and Safe Mucosal Adjuvants to Induce Humoral Immune Responses in Mice

There is currently an urgent need to develop safe and effective adjuvants for enhancing vaccine-induced antigen-specific immune responses. We demonstrate here that intranasal immunization with clinically used polypeptide antibiotics, polymyxin B (PMB) and colistin (CL), along with ovalbumin (OVA), i...

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Detalles Bibliográficos
Autores principales: Yoshino, Naoto, Endo, Masahiro, Kanno, Hiroyuki, Matsukawa, Naomi, Tsutsumi, Reiko, Takeshita, Ryosuke, Sato, Shigehiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623863/
https://www.ncbi.nlm.nih.gov/pubmed/23593492
http://dx.doi.org/10.1371/journal.pone.0061643

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