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In Vitro and In Vivo Effect of 5-FC Combined Gene Therapy with TNF-α and CD Suicide Gene on Human Laryngeal Carcinoma Cell Line Hep-2

This study was aimed to investigate the effect of combined cancer gene therapy with exogenous tumor necrosis factor-alpha (TNF-α) and cytosine deaminase (CD) suicide gene on laryngeal carcinoma cell line Hep-2 in vitro and in vivo. Transfection of the recombinant eukaryotic vectors of pcDNA3.1 (+) c...

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Detalles Bibliográficos
Autores principales: Chai, Li-Ping, Wang, Zhang-Feng, Liang, Wei-Ying, Chen, Lei, Chen, Dan, Wang, An-Xun, Zhang, Zhao-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623900/
https://www.ncbi.nlm.nih.gov/pubmed/23593411
http://dx.doi.org/10.1371/journal.pone.0061136