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Identification of a Functional Variant in the MICA Promoter Which Regulates MICA Expression and Increases HCV-Related Hepatocellular Carcinoma Risk

Hepatitis C virus (HCV) infection is the major cause of hepatocellular carcinoma (HCC) in Japan. We previously identified the association of SNP rs2596542 in the 5' flanking region of the MHC class I polypeptide-related sequence A (MICA) gene with the risk of HCV-induced HCC. In the current stu...

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Detalles Bibliográficos
Autores principales: Lo, Paulisally Hau Yi, Urabe, Yuji, Kumar, Vinod, Tanikawa, Chizu, Koike, Kazuhiko, Kato, Naoya, Miki, Daiki, Chayama, Kazuaki, Kubo, Michiaki, Nakamura, Yusuke, Matsuda, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623965/
https://www.ncbi.nlm.nih.gov/pubmed/23593449
http://dx.doi.org/10.1371/journal.pone.0061279