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CD1d-antibody fusion proteins target iNKT cells to the tumor and trigger long-term therapeutic responses
Despite the well-established antitumor activity of CD1d-restricted invariant natural killer T lymphocytes (iNKT), their use for cancer therapy has remained challenging. This appears to be due to their strong but short-lived activation followed by long-term anergy after a single administration of the...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer-Verlag
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3624007/ https://www.ncbi.nlm.nih.gov/pubmed/23242316 http://dx.doi.org/10.1007/s00262-012-1381-7 |