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Identification of the PGRMC1 protein complex as the putative sigma-2 receptor binding site

The sigma-2 receptor, whose gene remains to be cloned, has been validated as a biomarker for tumor cell proliferation. Here we report the use of a novel photoaffinity probe, WC-21, to identify the sigma-2 receptor binding site. WC-21, a sigma-2 ligand containing both a photoactive moiety azide and a...

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Detalles Bibliográficos
Autores principales: Xu, Jinbin, Zeng, Chenbo, Chu, Wenhua, Pan, Fenghui, Rothfuss, Justin M., Zhang, Fanjie, Tu, Zhude, Zhou, Dong, Zeng, Dexing, Vangveravong, Suwanna, Johnston, Fabian, Spitzer, Dirk, Chang, Katherine C., Hotchkiss, Richard S., Hawkins, William G., Wheeler, Kenneth T., Mach, Robert H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3624020/
https://www.ncbi.nlm.nih.gov/pubmed/21730960
http://dx.doi.org/10.1038/ncomms1386