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Identification of the PGRMC1 protein complex as the putative sigma-2 receptor binding site
The sigma-2 receptor, whose gene remains to be cloned, has been validated as a biomarker for tumor cell proliferation. Here we report the use of a novel photoaffinity probe, WC-21, to identify the sigma-2 receptor binding site. WC-21, a sigma-2 ligand containing both a photoactive moiety azide and a...
Autores principales: | Xu, Jinbin, Zeng, Chenbo, Chu, Wenhua, Pan, Fenghui, Rothfuss, Justin M., Zhang, Fanjie, Tu, Zhude, Zhou, Dong, Zeng, Dexing, Vangveravong, Suwanna, Johnston, Fabian, Spitzer, Dirk, Chang, Katherine C., Hotchkiss, Richard S., Hawkins, William G., Wheeler, Kenneth T., Mach, Robert H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3624020/ https://www.ncbi.nlm.nih.gov/pubmed/21730960 http://dx.doi.org/10.1038/ncomms1386 |
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