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Transcriptional data: a new gateway to drug repositioning?
Recent advances in computational biology suggest that any perturbation to the transcriptional programme of the cell can be summarised by a proper ‘signature’: a set of genes combined with a pattern of expression. Therefore, it should be possible to generate proxies of clinicopathological phenotypes...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Science Ltd. ;, Distributed by Virgin Mailing and Distribution
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625109/ https://www.ncbi.nlm.nih.gov/pubmed/22897878 http://dx.doi.org/10.1016/j.drudis.2012.07.014 |