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Structure-Function-Immunogenicity Studies of PfEMP1 Domain DBL2β(PF11_0521), a Malaria Parasite Ligand for ICAM-1
Plasmodium falciparum virulence has been ascribed to its ability to sequester in deep vascular beds, mediated by the variant surface antigen family PfEMP1 binding endothelial receptors like ICAM-1. We previously observed that naturally-acquired antibodies that block a PfEMP1 domain, DBL2β of PF11_05...
Autores principales: | Gullingsrud, Justin, Saveria, Tracy, Amos, Emily, Duffy, Patrick E., Oleinikov, Andrew V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625211/ https://www.ncbi.nlm.nih.gov/pubmed/23593462 http://dx.doi.org/10.1371/journal.pone.0061323 |
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