Fingolimod Phosphate Attenuates Oligomeric Amyloid β–Induced Neurotoxicity via Increased Brain-Derived Neurotrophic Factor Expression in Neurons

The neurodegenerative processes that underlie Alzheimer's disease are mediated, in part, by soluble oligomeric amyloid β, a neurotoxic protein that inhibits hippocampal long-term potentiation, disrupts synaptic plasticity, and induces the production of reactive oxygen species. Here we show that...

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Detalles Bibliográficos
Autores principales: Doi, Yukiko, Takeuchi, Hideyuki, Horiuchi, Hiroshi, Hanyu, Taketo, Kawanokuchi, Jun, Jin, Shijie, Parajuli, Bijay, Sonobe, Yoshifumi, Mizuno, Tetsuya, Suzumura, Akio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625222/
https://www.ncbi.nlm.nih.gov/pubmed/23593505
http://dx.doi.org/10.1371/journal.pone.0061988

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625222/
https://www.ncbi.nlm.nih.gov/pubmed/23593505
http://dx.doi.org/10.1371/journal.pone.0061988

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