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A member of the Ras oncogene family, RAP1A, mediates antileishmanial activity of monastrol

OBJECTIVES: To investigate the mode of action of monastrol in intracellular Leishmania. METHODS: Microarray experiments were conducted on an Affymetrix GeneChip(®) Human Genome U133 Plus 2.0 Array, to determine the genes that encode proteins related to pathological alterations of cell signalling pat...

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Detalles Bibliográficos
Autores principales: Kaur, Jaspreet, Dutta, Sujoy, Chang, Kwang-Poo, Singh, Neeloo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625431/
https://www.ncbi.nlm.nih.gov/pubmed/23292345
http://dx.doi.org/10.1093/jac/dks507