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Inflammasome in Intestinal Inflammation and Cancer

The activation of specific cytosolic pathogen recognition receptors, the nucleotide-binding-oligomerization-domain- (NOD-) like receptors (NLRs), leads to the assembly of the inflammasome, a multimeric complex platform that activates caspase-1. The caspase-1 pathway leads to the upregulation of impo...

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Detalles Bibliográficos
Autores principales: Nunes, Tiago, de Souza, Heitor S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625567/
https://www.ncbi.nlm.nih.gov/pubmed/23606794
http://dx.doi.org/10.1155/2013/654963