NBM-T-L-BMX-OS01, Semisynthesized from Osthole, Is a Novel Inhibitor of Histone Deacetylase and Enhances Learning and Memory in Rats

NBM-T-L-BMX-OS01 (BMX) was derived from the semisynthesis of osthole, isolated from Cnidium monnieri (L.) Cuss., and was identified to be a potent inhibitor of HDAC8. This study shows that HDAC8 is highly expressed in the pancreas and the brain. The function of HDAC8 in the brain has not been adequa...

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Detalles Bibliográficos
Autores principales: Yang, Ying-Chen, Chen, Chia-Nan, Wu, Carol-Imei, Huang, Wei-Jan, Kuo, Tsun-Yung, Kuan, Ming-Chung, Tsai, Tung-Hu, Huang, Jing-Shi, Huang, Chung-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625590/
https://www.ncbi.nlm.nih.gov/pubmed/23606881
http://dx.doi.org/10.1155/2013/514908

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