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Histone deacetylase inhibition reduces cardiac connexin43 expression and gap junction communication

Histone deacetylase inhibitors (HDACIs) are being investigated as novel therapies for cancer, inflammation, neurodegeneration, and heart failure. The effects of HDACIs on the functional expression of cardiac gap junctions (GJs) are essentially unknown. The purpose of this study was to determine the...

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Detalles Bibliográficos
Autores principales:	Xu, Qin, Lin, Xianming, Andrews, Laura, Patel, Dakshesh, Lampe, Paul D., Veenstra, Richard D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2013
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625725/ https://www.ncbi.nlm.nih.gov/pubmed/23596417 http://dx.doi.org/10.3389/fphar.2013.00044

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