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Male Breast Cancer: 37-Year Data Study at a Single Experience Center in Turkey

PURPOSE: The aim of this study is to evaluate the effects of prognostic factors on the overall survival (OS) and locoregional control (LC) among male breast cancer (MBC) patients treated at Cerrahpasa Medical School Hospital, along with a review of the related literature. METHODS: The data of 86 pat...

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Autores principales: Selcukbiricik, Fatih, Tural, Deniz, Aydoğan, Fatih, Beşe, Nuran, Büyükünal, Evin, Serdengeçti, Süheyla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Breast Cancer Society 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625771/
https://www.ncbi.nlm.nih.gov/pubmed/23593083
http://dx.doi.org/10.4048/jbc.2013.16.1.60
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author Selcukbiricik, Fatih
Tural, Deniz
Aydoğan, Fatih
Beşe, Nuran
Büyükünal, Evin
Serdengeçti, Süheyla
author_facet Selcukbiricik, Fatih
Tural, Deniz
Aydoğan, Fatih
Beşe, Nuran
Büyükünal, Evin
Serdengeçti, Süheyla
author_sort Selcukbiricik, Fatih
collection PubMed
description PURPOSE: The aim of this study is to evaluate the effects of prognostic factors on the overall survival (OS) and locoregional control (LC) among male breast cancer (MBC) patients treated at Cerrahpasa Medical School Hospital, along with a review of the related literature. METHODS: The data of 86 patients treated for MBC from 1973 to 2010 are retrospectively reviewed. Patient demographics and clinical information, including the date of diagnosis, treatment, clinical course, and the date and causes of death are routinely recorded. RESULTS: Median follow-up was 66 months. Isolated local-regional recurrence and distant metastases were observed in 15 (17.4%) and 24 (34.1%) of the cases, respectively. The 5-year OS rate was 65.8%; the disease-free survival rate was 72.4%, and the LC rate was 89.7%. The prognostic factors influencing local relapse were the T stage (p=0.002) and the chest wall muscular invasion (p=0.027) in the univariate analysis. The prognostic factors influencing OS were the presence of a positive axillary lymph node (p=0.001) and the T stage (p=0.001) in the univariate analysis. The T stage (p=0.008) and node (N) stage (p=0.038) were significant prognostic factors for OS in the multivariate analyses. Also, the T stage (p=0.034) was found to be significant for LC. CONCLUSION: We found that only the tumor size and lymph node status were independent prognostic factors for survival. In addition, only the tumor size was an independent prognostic factor for locoregional relapse. Modified radical mastectomy and conservative surgical procedures had similar outcomes for LC.
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spelling pubmed-36257712013-04-16 Male Breast Cancer: 37-Year Data Study at a Single Experience Center in Turkey Selcukbiricik, Fatih Tural, Deniz Aydoğan, Fatih Beşe, Nuran Büyükünal, Evin Serdengeçti, Süheyla J Breast Cancer Original Article PURPOSE: The aim of this study is to evaluate the effects of prognostic factors on the overall survival (OS) and locoregional control (LC) among male breast cancer (MBC) patients treated at Cerrahpasa Medical School Hospital, along with a review of the related literature. METHODS: The data of 86 patients treated for MBC from 1973 to 2010 are retrospectively reviewed. Patient demographics and clinical information, including the date of diagnosis, treatment, clinical course, and the date and causes of death are routinely recorded. RESULTS: Median follow-up was 66 months. Isolated local-regional recurrence and distant metastases were observed in 15 (17.4%) and 24 (34.1%) of the cases, respectively. The 5-year OS rate was 65.8%; the disease-free survival rate was 72.4%, and the LC rate was 89.7%. The prognostic factors influencing local relapse were the T stage (p=0.002) and the chest wall muscular invasion (p=0.027) in the univariate analysis. The prognostic factors influencing OS were the presence of a positive axillary lymph node (p=0.001) and the T stage (p=0.001) in the univariate analysis. The T stage (p=0.008) and node (N) stage (p=0.038) were significant prognostic factors for OS in the multivariate analyses. Also, the T stage (p=0.034) was found to be significant for LC. CONCLUSION: We found that only the tumor size and lymph node status were independent prognostic factors for survival. In addition, only the tumor size was an independent prognostic factor for locoregional relapse. Modified radical mastectomy and conservative surgical procedures had similar outcomes for LC. Korean Breast Cancer Society 2013-03 2013-03-31 /pmc/articles/PMC3625771/ /pubmed/23593083 http://dx.doi.org/10.4048/jbc.2013.16.1.60 Text en © 2013 Korean Breast Cancer Society. All rights reserved. http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Selcukbiricik, Fatih
Tural, Deniz
Aydoğan, Fatih
Beşe, Nuran
Büyükünal, Evin
Serdengeçti, Süheyla
Male Breast Cancer: 37-Year Data Study at a Single Experience Center in Turkey
title Male Breast Cancer: 37-Year Data Study at a Single Experience Center in Turkey
title_full Male Breast Cancer: 37-Year Data Study at a Single Experience Center in Turkey
title_fullStr Male Breast Cancer: 37-Year Data Study at a Single Experience Center in Turkey
title_full_unstemmed Male Breast Cancer: 37-Year Data Study at a Single Experience Center in Turkey
title_short Male Breast Cancer: 37-Year Data Study at a Single Experience Center in Turkey
title_sort male breast cancer: 37-year data study at a single experience center in turkey
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625771/
https://www.ncbi.nlm.nih.gov/pubmed/23593083
http://dx.doi.org/10.4048/jbc.2013.16.1.60
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