In vivo evaluation of edge-loading in metal-on-metal hip resurfacing patients with pseudotumours

OBJECTIVES: Pseudotumours (abnormal peri-prosthetic soft-tissue reactions) following metal-on-metal hip resurfacing arthroplasty (MoMHRA) have been associated with elevated metal ion levels, suggesting that excessive wear may occur due to edge-loading of these MoM implants. This study aimed to quant...

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Autores principales: Kwon, Y-M., Mellon, S. J., Monk, P., Murray, D. W., Gill, H. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: British Editorial Society of Bone and Joint Surgery 2012
Materias:
Hip
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626206/
https://www.ncbi.nlm.nih.gov/pubmed/23610670
http://dx.doi.org/10.1302/2046-3758.14.2000019
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author Kwon, Y-M.
Mellon, S. J.
Monk, P.
Murray, D. W.
Gill, H. S.
author_facet Kwon, Y-M.
Mellon, S. J.
Monk, P.
Murray, D. W.
Gill, H. S.
author_sort Kwon, Y-M.
collection PubMed
description OBJECTIVES: Pseudotumours (abnormal peri-prosthetic soft-tissue reactions) following metal-on-metal hip resurfacing arthroplasty (MoMHRA) have been associated with elevated metal ion levels, suggesting that excessive wear may occur due to edge-loading of these MoM implants. This study aimed to quantify in vivo edge-loading in MoMHRA patients with and without pseudotumours during functional activities. METHODS: The duration and magnitude of edge-loading in vivo was quantified during functional activities by combining the dynamic hip joint segment contact force calculated from the three-dimensional (3D) motion analysis system with the 3D reconstruction of orientation of the acetabular component and each patient’s specific hip joint centre, based on CT scans. RESULTS: Edge-loading in the hips with pseudotumours occurred with a four-fold increase in duration and magnitude of force compared with the hips without pseudotumours (p = 0.02). CONCLUSIONS: The study provides the first in vivo evidence to support that edge-loading is an important mechanism that leads to localised excessive wear (edge-wear), with subsequent elevation of metal ion levels in MoMHRA patients with pseudotumours.
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spelling pubmed-36262062013-04-22 In vivo evaluation of edge-loading in metal-on-metal hip resurfacing patients with pseudotumours Kwon, Y-M. Mellon, S. J. Monk, P. Murray, D. W. Gill, H. S. Bone Joint Res Hip OBJECTIVES: Pseudotumours (abnormal peri-prosthetic soft-tissue reactions) following metal-on-metal hip resurfacing arthroplasty (MoMHRA) have been associated with elevated metal ion levels, suggesting that excessive wear may occur due to edge-loading of these MoM implants. This study aimed to quantify in vivo edge-loading in MoMHRA patients with and without pseudotumours during functional activities. METHODS: The duration and magnitude of edge-loading in vivo was quantified during functional activities by combining the dynamic hip joint segment contact force calculated from the three-dimensional (3D) motion analysis system with the 3D reconstruction of orientation of the acetabular component and each patient’s specific hip joint centre, based on CT scans. RESULTS: Edge-loading in the hips with pseudotumours occurred with a four-fold increase in duration and magnitude of force compared with the hips without pseudotumours (p = 0.02). CONCLUSIONS: The study provides the first in vivo evidence to support that edge-loading is an important mechanism that leads to localised excessive wear (edge-wear), with subsequent elevation of metal ion levels in MoMHRA patients with pseudotumours. British Editorial Society of Bone and Joint Surgery 2012-04-01 /pmc/articles/PMC3626206/ /pubmed/23610670 http://dx.doi.org/10.1302/2046-3758.14.2000019 Text en ©2012 British Editorial Society of Bone and Joint Surgery This is an open-access article distributed under the terms of the Creative Commons Attributions licence, which permits unrestricted use, distribution, and reproduction in any medium, but not for commercial gain, provided the original author and source are credited.
spellingShingle Hip
Kwon, Y-M.
Mellon, S. J.
Monk, P.
Murray, D. W.
Gill, H. S.
In vivo evaluation of edge-loading in metal-on-metal hip resurfacing patients with pseudotumours
title In vivo evaluation of edge-loading in metal-on-metal hip resurfacing patients with pseudotumours
title_full In vivo evaluation of edge-loading in metal-on-metal hip resurfacing patients with pseudotumours
title_fullStr In vivo evaluation of edge-loading in metal-on-metal hip resurfacing patients with pseudotumours
title_full_unstemmed In vivo evaluation of edge-loading in metal-on-metal hip resurfacing patients with pseudotumours
title_short In vivo evaluation of edge-loading in metal-on-metal hip resurfacing patients with pseudotumours
title_sort in vivo evaluation of edge-loading in metal-on-metal hip resurfacing patients with pseudotumours
topic Hip
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626206/
https://www.ncbi.nlm.nih.gov/pubmed/23610670
http://dx.doi.org/10.1302/2046-3758.14.2000019
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AT murraydw invivoevaluationofedgeloadinginmetalonmetalhipresurfacingpatientswithpseudotumours
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