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Local inhibition of 5-lipoxygenase enhances bone formation in a rat model

OBJECTIVES: Recent studies have shown that modulating inflammation-related lipid signalling after a bone fracture can accelerate healing in animal models. Specifically, decreasing 5-lipoxygenase (5-LO) activity during fracture healing increases cyclooxygenase-2 (COX-2) expression in the fracture cal...

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Detalles Bibliográficos
Autores principales:	Cottrell, J. A., Keshav, V., Mitchell, A., O’Connor, J. P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	British Editorial Society of Bone and Joint Surgery 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626215/ https://www.ncbi.nlm.nih.gov/pubmed/23610701 http://dx.doi.org/10.1302/2046-3758.22.2000066

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