Cargando…
Arginine-based cationic liposomes for efficient in vitro plasmid DNA delivery with low cytotoxicity
BACKGROUND: Currently available gene delivery vehicles have many limitations such as low gene delivery efficiency and high cytotoxicity. To overcome these drawbacks, we designed and synthesized two cationic lipids comprised of n-tetradecyl alcohol as the hydrophobic moiety, 3-hydrocarbon chain as th...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Dove Medical Press
2013
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626367/ https://www.ncbi.nlm.nih.gov/pubmed/23630419 http://dx.doi.org/10.2147/IJN.S38903 |