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Large bilateral foveal cysts in the inner retina of a patient treated with tamoxifen, diagnosed with Fourier-domain optical coherence tomography
PURPOSE: To report a case of a patient receiving tamoxifen with visual deterioration and describe the unusual optical coherence tomography (OCT) findings. METHOD: Observational case report. RESULTS: A 55-year-old female patient was referred to our department complaining of gradual visual deteriorati...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626412/ https://www.ncbi.nlm.nih.gov/pubmed/23630411 http://dx.doi.org/10.2147/OPTH.S38951 |
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author | Georgalas, Ilias Paraskevopoulos, Theodore Papaconstaninou, Dimitris Brouzas, Dimitiris Koutsandrea, Chryssanthi |
author_facet | Georgalas, Ilias Paraskevopoulos, Theodore Papaconstaninou, Dimitris Brouzas, Dimitiris Koutsandrea, Chryssanthi |
author_sort | Georgalas, Ilias |
collection | PubMed |
description | PURPOSE: To report a case of a patient receiving tamoxifen with visual deterioration and describe the unusual optical coherence tomography (OCT) findings. METHOD: Observational case report. RESULTS: A 55-year-old female patient was referred to our department complaining of gradual visual deterioration in both eyes. Medical history was unremarkable apart from breast cancer for which she had received tamoxifen for 10 years (mean dosage 20 mg/day). Best corrected visual acuity was 20/400 in her right eye and 20/40 in her left eye. Fundoscopy in both eyes was without any obvious signs of maculopathy. However, Fourier-domain OCT demonstrated bilateral extensive areas of disruption in inner retinal layers without any signs of crystalline retinopathy. Six months after the cessation of tamoxifen, the situation remains unchanged. CONCLUSION: Patients receiving tamoxifen should be monitored with high-resolution OCT for fundoscopically invisible changes in the inner retinal layers, the progression of which may seriously affect the patient’s vision and subsequently their quality of life. |
format | Online Article Text |
id | pubmed-3626412 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-36264122013-04-29 Large bilateral foveal cysts in the inner retina of a patient treated with tamoxifen, diagnosed with Fourier-domain optical coherence tomography Georgalas, Ilias Paraskevopoulos, Theodore Papaconstaninou, Dimitris Brouzas, Dimitiris Koutsandrea, Chryssanthi Clin Ophthalmol Case Report PURPOSE: To report a case of a patient receiving tamoxifen with visual deterioration and describe the unusual optical coherence tomography (OCT) findings. METHOD: Observational case report. RESULTS: A 55-year-old female patient was referred to our department complaining of gradual visual deterioration in both eyes. Medical history was unremarkable apart from breast cancer for which she had received tamoxifen for 10 years (mean dosage 20 mg/day). Best corrected visual acuity was 20/400 in her right eye and 20/40 in her left eye. Fundoscopy in both eyes was without any obvious signs of maculopathy. However, Fourier-domain OCT demonstrated bilateral extensive areas of disruption in inner retinal layers without any signs of crystalline retinopathy. Six months after the cessation of tamoxifen, the situation remains unchanged. CONCLUSION: Patients receiving tamoxifen should be monitored with high-resolution OCT for fundoscopically invisible changes in the inner retinal layers, the progression of which may seriously affect the patient’s vision and subsequently their quality of life. Dove Medical Press 2013 2013-04-10 /pmc/articles/PMC3626412/ /pubmed/23630411 http://dx.doi.org/10.2147/OPTH.S38951 Text en © 2013 Georgalas et al, publisher and licensee Dove Medical Press Ltd This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited. |
spellingShingle | Case Report Georgalas, Ilias Paraskevopoulos, Theodore Papaconstaninou, Dimitris Brouzas, Dimitiris Koutsandrea, Chryssanthi Large bilateral foveal cysts in the inner retina of a patient treated with tamoxifen, diagnosed with Fourier-domain optical coherence tomography |
title | Large bilateral foveal cysts in the inner retina of a patient treated with tamoxifen, diagnosed with Fourier-domain optical coherence tomography |
title_full | Large bilateral foveal cysts in the inner retina of a patient treated with tamoxifen, diagnosed with Fourier-domain optical coherence tomography |
title_fullStr | Large bilateral foveal cysts in the inner retina of a patient treated with tamoxifen, diagnosed with Fourier-domain optical coherence tomography |
title_full_unstemmed | Large bilateral foveal cysts in the inner retina of a patient treated with tamoxifen, diagnosed with Fourier-domain optical coherence tomography |
title_short | Large bilateral foveal cysts in the inner retina of a patient treated with tamoxifen, diagnosed with Fourier-domain optical coherence tomography |
title_sort | large bilateral foveal cysts in the inner retina of a patient treated with tamoxifen, diagnosed with fourier-domain optical coherence tomography |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626412/ https://www.ncbi.nlm.nih.gov/pubmed/23630411 http://dx.doi.org/10.2147/OPTH.S38951 |
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