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Single-cell sequencing analysis characterizes common and cell-lineage-specific mutations in a muscle-invasive bladder cancer

BACKGROUND: Cancers arise through an evolutionary process in which cell populations are subjected to selection; however, to date, the process of bladder cancer, which is one of the most common cancers in the world, remains unknown at a single-cell level. RESULTS: We carried out single-cell exome seq...

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Detalles Bibliográficos
Autores principales: Li, Yingrui, Xu, Xun, Song, Luting, Hou, Yong, Li, Zesong, Tsang, Shirley, Li, Fuqiang, Im, Kate McGee, Wu, Kui, Wu, Hanjie, Ye, Xiaofei, Li, Guibo, Wang, Linlin, Zhang, Bo, Liang, Jie, Xie, Wei, Wu, Renhua, Jiang, Hui, Liu, Xiao, Yu, Chang, Zheng, Hancheng, Jian, Min, Nie, Liping, Wan, Lei, Shi, Min, Sun, Xiaojuan, Tang, Aifa, Guo, Guangwu, Gui, Yaoting, Cai, Zhiming, Li, Jingxiang, Wang, Wen, Lu, Zuhong, Zhang, Xiuqing, Bolund, Lars, Kristiansen, Karsten, Wang, Jian, Yang, Huanming, Dean, Michael, Wang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626503/
https://www.ncbi.nlm.nih.gov/pubmed/23587365
http://dx.doi.org/10.1186/2047-217X-1-12