Glutamate 83 and arginine 85 of helix H3 bend are key residues for FtsZ polymerization, GTPase activity and cellular viability of Escherichia coli: lateral mutations affect FtsZ polymerization and E. coli viability

BACKGROUND: FtsZ is an essential cell division protein, which localizes at the middle of the bacterial cell to mediate cytokinesis. In vitro, FtsZ polymerizes and induces GTPase activity through longitudinal interactions to form the protofilaments, whilst lateral interactions result within formation...

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Detalles Bibliográficos
Autores principales: Shin, Jae Yen, Vollmer, Waldemar, Lagos, Rosalba, Monasterio, Octavio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626584/
https://www.ncbi.nlm.nih.gov/pubmed/23384248
http://dx.doi.org/10.1186/1471-2180-13-26

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