Dynasore Protects Mitochondria and Improves Cardiac Lusitropy in Langendorff Perfused Mouse Heart

BACKGROUND: Heart failure due to diastolic dysfunction exacts a major economic, morbidity and mortality burden in the United States. Therapeutic agents to improve diastolic dysfunction are limited. It was recently found that Dynamin related protein 1 (Drp1) mediates mitochondrial fission during isch...

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Detalles Bibliográficos
Autores principales: Gao, Danchen, Zhang, Li, Dhillon, Ranvir, Hong, Ting-Ting, Shaw, Robin M., Zhu, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626591/
https://www.ncbi.nlm.nih.gov/pubmed/23596510
http://dx.doi.org/10.1371/journal.pone.0060967

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626591/
https://www.ncbi.nlm.nih.gov/pubmed/23596510
http://dx.doi.org/10.1371/journal.pone.0060967

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