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The C-Type Lectin of the Aggrecan G3 Domain Activates Complement
Excessive complement activation contributes to joint diseases such as rheumatoid arthritis and osteoarthritis during which cartilage proteins are fragmented and released into the synovial fluid. Some of these proteins and fragments activate complement, which may sustain inflammation. The G3 domain o...
Autores principales: | Melin Fürst, Camilla, Mörgelin, Matthias, Vadstrup, Kasper, Heinegård, Dick, Aspberg, Anders, Blom, Anna M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626604/ https://www.ncbi.nlm.nih.gov/pubmed/23596522 http://dx.doi.org/10.1371/journal.pone.0061407 |
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