Disruption of the Sec24d Gene Results in Early Embryonic Lethality in the Mouse

Transport of newly synthesized proteins from the endoplasmic reticulum (ER) to the Golgi is mediated by the coat protein complex COPII. The inner coat of COPII is assembled from heterodimers of SEC23 and SEC24. Though mice with mutations in one of the four Sec24 paralogs, Sec24b, exhibit a neural tu...

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Detalles Bibliográficos
Autores principales: Baines, Andrea C., Adams, Elizabeth J., Zhang, Bin, Ginsburg, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626607/
https://www.ncbi.nlm.nih.gov/pubmed/23596517
http://dx.doi.org/10.1371/journal.pone.0061114

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