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Multi-target action of the novel anti-Alzheimer compound CHF5074: in vivo study of long term treatment in Tg2576 mice

BACKGROUND: Alzheimer disease is a multifactorial disorder characterized by the progressive deterioration of neuronal networks. The pathological hallmarks includes extracellular amyloid plaques and intraneuronal neurofibrillary tangles, but the primary cause is only partially understood. Thus, there...

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Detalles Bibliográficos
Autores principales:	Sivilia, Sandra, Lorenzini, Luca, Giuliani, Alessandro, Gusciglio, Marco, Fernandez, Mercedes, Baldassarro, Vito Antonio, Mangano, Chiara, Ferraro, Luca, Pietrini, Vladimiro, Baroc, Maria Francesca, Viscomi, Arturo R, Ottonello, Simone, Villetti, Gino, Imbimbo, Bruno P, Calzà, Laura, Giardino, Luciana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626610/ https://www.ncbi.nlm.nih.gov/pubmed/23560952 http://dx.doi.org/10.1186/1471-2202-14-44

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