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Synthetic immunotherapy induces HIV virus specific Th1 cytotoxic response and death of an HIV-1 infected human cell line through classic complement activation

BACKGROUND: This manuscript describes the development of a novel synthetic immunotherapy (HIV-v) composed of four multi-epitope polypeptides targeting conserved regions in the Nef, Rev, Vif and Vpr viral proteins. Immunogenicity and cytotoxicity of HIV-v are discussed. METHODS: Short conserved T-cel...

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Detalles Bibliográficos
Autores principales:	Pleguezuelos, Olga, Stoloff, Gregory A, Caparrós-Wanderley, Wilson
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626621/ https://www.ncbi.nlm.nih.gov/pubmed/23557359 http://dx.doi.org/10.1186/1743-422X-10-107

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