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Cotrimoxazole plasma levels, dialyzer clearance and total removal by extended dialysis in a patient with acute kidney injury: risk of under-dosing using current dosing recommendations

BACKGROUND: Dosing of antibiotics in critically ill patients is challenging. It becomes even more difficult if renal or hepatic impairment ensue. Modern means of renal replacement therapy are capable of removing antibiotics to a higher rate than decades ago, leaving clinicians with a high degree of...

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Detalles Bibliográficos
Autores principales: Clajus, Christian, Kühn-Velten, W Nikolaus, Schmidt, Julius J, Lorenzen, Johan M, Pietsch, Daniel, Beutel, Gernot, Kielstein, Jan T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626772/
https://www.ncbi.nlm.nih.gov/pubmed/23551893
http://dx.doi.org/10.1186/2050-6511-14-19