Phase I study of OM-174, a lipid A analogue, with assessment of immunological response, in patients with refractory solid tumors

BACKGROUND: Lipids A, the lipophilic partial structure of lipopolysaccharides, induce regression of several tumor types in animal models. Rather than exerting direct cytotoxic effect, these compounds trigger the immune system which in turn stimulates secretion of cytokines, and activates the inducib...

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Detalles Bibliográficos
Autores principales: Isambert, Nicolas, Fumoleau, Pierre, Paul, Catherine, Ferrand, Christophe, Zanetta, Sylvie, Bauer, Jacques, Ragot, Kevin, Lizard, Gérard, Jeannin, Jean-François, Bardou, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626800/
https://www.ncbi.nlm.nih.gov/pubmed/23547558
http://dx.doi.org/10.1186/1471-2407-13-172

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