A robust and efficient statistical method for genetic association studies using case and control samples from multiple cohorts

BACKGROUND: The theoretical basis of genome-wide association studies (GWAS) is statistical inference of linkage disequilibrium (LD) between any polymorphic marker and a putative disease locus. Most methods widely implemented for such analyses are vulnerable to several key demographic factors and del...

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Detalles Bibliográficos
Autores principales: Wang, Minghui, Wang, Lin, Jiang, Ning, Jia, Tianye, Luo, Zewei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626840/
https://www.ncbi.nlm.nih.gov/pubmed/23394771
http://dx.doi.org/10.1186/1471-2164-14-88

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