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Digital sorting of complex tissues for cell type-specific gene expression profiles

BACKGROUND: Cellular heterogeneity is present in almost all gene expression profiles. However, transcriptome analysis of tissue specimens often ignores the cellular heterogeneity present in these samples. Standard deconvolution algorithms require prior knowledge of the cell type frequencies within a...

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Detalles Bibliográficos
Autores principales:	Zhong, Yi, Wan, Ying-Wooi, Pang, Kaifang, Chow, Lionel ML, Liu, Zhandong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626856/ https://www.ncbi.nlm.nih.gov/pubmed/23497278 http://dx.doi.org/10.1186/1471-2105-14-89

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