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LKB1 and AMPK and the cancer-metabolism link - ten years after

The identification of a complex containing the tumor suppressor LKB1 as the critical upstream kinase required for the activation of AMP-activated protein kinase (AMPK) by metabolic stress was reported in an article in Journal of Biology in 2003. This finding represented the first clear link between...

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Detalles Bibliográficos
Autores principales: Hardie, D Grahame, Alessi, Dario R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626889/
https://www.ncbi.nlm.nih.gov/pubmed/23587167
http://dx.doi.org/10.1186/1741-7007-11-36