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LKB1 and AMPK and the cancer-metabolism link - ten years after
The identification of a complex containing the tumor suppressor LKB1 as the critical upstream kinase required for the activation of AMP-activated protein kinase (AMPK) by metabolic stress was reported in an article in Journal of Biology in 2003. This finding represented the first clear link between...
Autores principales: | Hardie, D Grahame, Alessi, Dario R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626889/ https://www.ncbi.nlm.nih.gov/pubmed/23587167 http://dx.doi.org/10.1186/1741-7007-11-36 |
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