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Resuscitative strategies in traumatic hemorrhagic shock

Managing trauma patients with hemorrhagic shock is complex and difficult. Despite our knowledge of the pathophysiology of hemorrhagic shock in trauma patients that we have accumulated during recent decades, the mortality rate of these patients remains high. In the acute phase of hemorrhage, the ther...

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Detalles Bibliográficos
Autores principales: Bouglé, Adrien, Harrois, Anatole, Duranteau, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626904/
https://www.ncbi.nlm.nih.gov/pubmed/23311726
http://dx.doi.org/10.1186/2110-5820-3-1
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author Bouglé, Adrien
Harrois, Anatole
Duranteau, Jacques
author_facet Bouglé, Adrien
Harrois, Anatole
Duranteau, Jacques
author_sort Bouglé, Adrien
collection PubMed
description Managing trauma patients with hemorrhagic shock is complex and difficult. Despite our knowledge of the pathophysiology of hemorrhagic shock in trauma patients that we have accumulated during recent decades, the mortality rate of these patients remains high. In the acute phase of hemorrhage, the therapeutic priority is to stop the bleeding as quickly as possible. As long as this bleeding is uncontrolled, the physician must maintain oxygen delivery to limit tissue hypoxia, inflammation, and organ dysfunction. This process involves fluid resuscitation, the use of vasopressors, and blood transfusion to prevent or correct acute coagulopathy of trauma. The optimal resuscitative strategy is controversial. To move forward, we need to establish optimal therapeutic approaches with clear objectives for fluid resuscitation, blood pressure, and hemoglobin levels to guide resuscitation and limit the risk of fluid overload and transfusion.
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spelling pubmed-36269042013-04-16 Resuscitative strategies in traumatic hemorrhagic shock Bouglé, Adrien Harrois, Anatole Duranteau, Jacques Ann Intensive Care Review Managing trauma patients with hemorrhagic shock is complex and difficult. Despite our knowledge of the pathophysiology of hemorrhagic shock in trauma patients that we have accumulated during recent decades, the mortality rate of these patients remains high. In the acute phase of hemorrhage, the therapeutic priority is to stop the bleeding as quickly as possible. As long as this bleeding is uncontrolled, the physician must maintain oxygen delivery to limit tissue hypoxia, inflammation, and organ dysfunction. This process involves fluid resuscitation, the use of vasopressors, and blood transfusion to prevent or correct acute coagulopathy of trauma. The optimal resuscitative strategy is controversial. To move forward, we need to establish optimal therapeutic approaches with clear objectives for fluid resuscitation, blood pressure, and hemoglobin levels to guide resuscitation and limit the risk of fluid overload and transfusion. Springer 2013-01-12 /pmc/articles/PMC3626904/ /pubmed/23311726 http://dx.doi.org/10.1186/2110-5820-3-1 Text en Copyright ©2013 Bouglé et al.; licensee Springer. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Bouglé, Adrien
Harrois, Anatole
Duranteau, Jacques
Resuscitative strategies in traumatic hemorrhagic shock
title Resuscitative strategies in traumatic hemorrhagic shock
title_full Resuscitative strategies in traumatic hemorrhagic shock
title_fullStr Resuscitative strategies in traumatic hemorrhagic shock
title_full_unstemmed Resuscitative strategies in traumatic hemorrhagic shock
title_short Resuscitative strategies in traumatic hemorrhagic shock
title_sort resuscitative strategies in traumatic hemorrhagic shock
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626904/
https://www.ncbi.nlm.nih.gov/pubmed/23311726
http://dx.doi.org/10.1186/2110-5820-3-1
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