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Safety and efficacy of everolimus in Chinese patients with metastatic renal cell carcinoma resistant to vascular endothelial growth factor receptor-tyrosine kinase inhibitor therapy: an open-label phase 1b study
BACKGROUND: In China, there are currently no approved therapies for the treatment of metastatic renal cell carcinoma (mRCC) following progression with vascular endothelial growth factor (VEGF)-targeted agents. In the phase 3 RECORD-1 trial, the mammalian target of rapamycin (mTOR) inhibitor everolim...
Autores principales: | Guo, Jun, Huang, Yiran, Zhang, Xu, Zhou, Fangjian, Sun, Yinghao, Qin, Shukui, Ye, Zhangqun, Wang, Hui, Jappe, Annette, Straub, Patrick, Pirotta, Nicoletta, Gogov, Sven |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626915/ https://www.ncbi.nlm.nih.gov/pubmed/23514360 http://dx.doi.org/10.1186/1471-2407-13-136 |
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