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Xentry, a new class of cell-penetrating peptide uniquely equipped for delivery of drugs

Here we describe an entirely new class of cell-penetrating peptide (CPP) represented by the short peptide Xentry (LCLRPVG) derived from an N-terminal region of the X-protein of the hepatitis B virus. Xentry permeates adherent cells using syndecan-4 as a portal for entry, and is uniquely restricted f...

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Detalles Bibliográficos
Autores principales: Montrose, Kristopher, Yang, Yi, Sun, Xueying, Wiles, Siouxsie, Krissansen, Geoffrey W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627194/
https://www.ncbi.nlm.nih.gov/pubmed/23588666
http://dx.doi.org/10.1038/srep01661