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The BAFF Receptor Transduces Survival Signals by Co-opting the B Cell Receptor Signaling Pathway

Follicular B cell survival requires signaling from BAFFR, a receptor for BAFF and the B cell antigen receptor (BCR). This “tonic” BCR survival signal is distinct from that induced by antigen binding and may be ligand-independent. We show that inducible inactivation of the Syk tyrosine kinase, a key...

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Detalles Bibliográficos
Autores principales:	Schweighoffer, Edina, Vanes, Lesley, Nys, Josquin, Cantrell, Doreen, McCleary, Scott, Smithers, Nicholas, Tybulewicz, Victor L.J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627223/ https://www.ncbi.nlm.nih.gov/pubmed/23453634 http://dx.doi.org/10.1016/j.immuni.2012.11.015

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