Inhibitors of HIV-1 Reverse Transcriptase—Associated Ribonuclease H Activity

HIV-1 enzyme reverse transcriptase (RT) is a major target for antiviral drug development, with over half of current FDA-approved therapeutics against HIV infection targeting the DNA polymerase activity of this enzyme. HIV-1 RT is a multifunctional enzyme that has RNA and DNA dependent polymerase act...

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Detalles Bibliográficos
Autores principales: Ilina, Tatiana, LaBarge, Krystal, Sarafianos, Stefan G., Ishima, Rieko, Parniak, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627382/
https://www.ncbi.nlm.nih.gov/pubmed/23599900
http://dx.doi.org/10.3390/biology1030521

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627382/
https://www.ncbi.nlm.nih.gov/pubmed/23599900
http://dx.doi.org/10.3390/biology1030521

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