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In vitro and in vivo evaluation of a sublingual fentanyl wafer formulation
BACKGROUND: The objective of this study was to prepare a novel fentanyl wafer formulation by a freeze-drying method, and to evaluate its in vitro and in vivo release characteristics, including its bioavailability via the sublingual route. METHODS: The wafer formulation was prepared by freeze-drying...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Dove Medical Press
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627472/ https://www.ncbi.nlm.nih.gov/pubmed/23596347 http://dx.doi.org/10.2147/DDDT.S42619 |