Mutations in LRRC50 Predispose Zebrafish and Humans to Seminomas

Seminoma is a subclass of human testicular germ cell tumors (TGCT), the most frequently observed cancer in young men with a rising incidence. Here we describe the identification of a novel gene predisposing specifically to seminoma formation in a vertebrate model organism. Zebrafish carrying a heter...

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Detalles Bibliográficos
Autores principales: Basten, Sander G., Davis, Erica E., Gillis, Ad J. M., van Rooijen, Ellen, Stoop, Hans, Babala, Nikolina, Logister, Ive, Heath, Zachary G., Jonges, Trudy N., Katsanis, Nicholas, Voest, Emile E., van Eeden, Freek J., Medema, Rene H., Ketting, René F., Schulte-Merker, Stefan, Looijenga, Leendert H. J., Giles, Rachel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627517/
https://www.ncbi.nlm.nih.gov/pubmed/23599692
http://dx.doi.org/10.1371/journal.pgen.1003384

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