Cargando…
Unconventional miR-122 binding stabilizes the HCV genome by forming a trimolecular RNA structure
MicroRNAs (miRNAs) typically downregulate protein expression from target mRNAs through limited base-pairing interactions between the 5′ ‘seed’ region of the miRNA and the mRNA 3′ untranslated region (3′UTR). In contrast to this established mode of action, the liver-specific human miR-122 binds at tw...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2013
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627571/ https://www.ncbi.nlm.nih.gov/pubmed/23416544 http://dx.doi.org/10.1093/nar/gkt075 |