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Quantitative analysis of TALE–DNA interactions suggests polarity effects

Transcription activator-like effectors (TALEs) have revolutionized the field of genome engineering. We present here a systematic assessment of TALE DNA recognition, using quantitative electrophoretic mobility shift assays and reporter gene activation assays. Within TALE proteins, tandem 34-amino aci...

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Detalles Bibliográficos
Autores principales:	Meckler, Joshua F., Bhakta, Mital S., Kim, Moon-Soo, Ovadia, Robert, Habrian, Chris H., Zykovich, Artem, Yu, Abigail, Lockwood, Sarah H., Morbitzer, Robert, Elsäesser, Janett, Lahaye, Thomas, Segal, David J., Baldwin, Enoch P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2013
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627578/ https://www.ncbi.nlm.nih.gov/pubmed/23408851 http://dx.doi.org/10.1093/nar/gkt085

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