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Efficient identification of rare variants in large populations: deep re-sequencing the CRP locus in the CARDIA study
Effect sizes of many common single nucleotide polymorphisms identified in genome-wide association studies generally explain only a modest fraction of the total estimated heritability in a variety of traits. One hypothesis is that rare variants with larger effects might account for the missing herita...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627584/ https://www.ncbi.nlm.nih.gov/pubmed/23408856 http://dx.doi.org/10.1093/nar/gkt092 |