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Single-molecule chemical denaturation of riboswitches

To date, single-molecule RNA science has been developed almost exclusively around the effect of metal ions as folding promoters and stabilizers of the RNA structure. Here, we introduce a novel strategy that combines single-molecule Förster resonance energy transfer (FRET) and chemical denaturation t...

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Detalles Bibliográficos
Autores principales:	Dalgarno, Paul A., Bordello, Jorge, Morris, Rhodri, St-Pierre, Patrick, Dubé, Audrey, Samuel, Ifor D. W., Lafontaine, Daniel A., Penedo, J. Carlos
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2013
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627600/ https://www.ncbi.nlm.nih.gov/pubmed/23446276 http://dx.doi.org/10.1093/nar/gkt128

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