Cargando…

Human SIRT1 regulates DNA binding and stability of the Mcm10 DNA replication factor via deacetylation

The eukaryotic DNA replication initiation factor Mcm10 is essential for both replisome assembly and function. Human Mcm10 has two DNA-binding domains, the conserved internal domain (ID) and the C-terminal domain (CTD), which is specific to metazoans. SIRT1 is a nicotinamide adenine dinucleotide (NAD...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fatoba, Samuel T., Tognetti, Silvia, Berto, Melissa, Leo, Elisabetta, Mulvey, Claire M., Godovac-Zimmermann, Jasminka, Pommier, Yves, Okorokov, Andrei L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2013
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627603/ https://www.ncbi.nlm.nih.gov/pubmed/23449222 http://dx.doi.org/10.1093/nar/gkt131

Ejemplares similares

The human GINS complex associates with Cdc45 and MCM and is essential for DNA replication
por: Aparicio, Tomás, et al.
Publicado: (2009)

DNA-PK is activated by SIRT2 deacetylation to promote DNA double-strand break repair by non-homologous end joining
por: Head, PamelaSara E, et al.
Publicado: (2023)

Chromosome-wide histone deacetylation by sirtuins prevents hyperactivation of DNA damage-induced signaling upon replicative stress
por: Simoneau, Antoine, et al.
Publicado: (2016)

Novel roles of HP1a and Mcm10 in DNA replication, genome maintenance and photoreceptor cell differentiation
por: Vo, Nicole, et al.
Publicado: (2017)

Phosphorylation of Mcm2 modulates Mcm2–7 activity and affects the cell’s response to DNA damage
por: Stead, Brent E., et al.
Publicado: (2011)

Deregulated Cdc6 inhibits DNA replication and suppresses Cdc7-mediated phosphorylation of Mcm2–7 complex
por: Kundu, Lena R., et al.
Publicado: (2010)

SIRT1 deacetylates APE1 and regulates cellular base excision repair
por: Yamamori, Tohru, et al.
Publicado: (2010)

The ORC/Cdc6/MCM2-7 complex facilitates MCM2-7 dimerization during prereplicative complex formation
por: Evrin, Cecile, et al.
Publicado: (2014)

Evidence for lesion bypass by yeast replicative DNA polymerases during DNA damage
por: Sabouri, Nasim, et al.
Publicado: (2008)

Potent DNA strand annealing activity associated with mouse Mcm2∼7 heterohexameric complex
por: You, Zhiying, et al.
Publicado: (2017)

The importance of nuclear RAGE–Mcm2 axis in diabetes or cancer-associated replication stress
por: Han, Zhe, et al.
Publicado: (2023)

The N-terminus of Mcm10 is important for interaction with the 9-1-1 clamp and in resistance to DNA damage
por: Alver, Robert C., et al.
Publicado: (2014)

The Saccharomyces cerevisiae Mcm6/2 and Mcm5/3 ATPase active sites contribute to the function of the putative Mcm2-7 ‘gate’
por: Bochman, Matthew L., et al.
Publicado: (2010)

Mechano-chemical kinetics of DNA replication: identification of the translocation step of a replicative DNA polymerase
por: Morin, José A., et al.
Publicado: (2015)

UBR5 interacts with the replication fork and protects DNA replication from DNA polymerase η toxicity
por: Cipolla, Lina, et al.
Publicado: (2019)

Steric exclusion and wrapping of the excluded DNA strand occurs along discrete external binding paths during MCM helicase unwinding
por: Graham, Brian W., et al.
Publicado: (2011)

RAD51 interconnects between DNA replication, DNA repair and immunity
por: Bhattacharya, Souparno, et al.
Publicado: (2017)

DNA-dependent protease activity of human Spartan facilitates replication of DNA–protein crosslink-containing DNA
por: Mórocz, Mónika, et al.
Publicado: (2017)

SIRT6 coordinates with CHD4 to promote chromatin relaxation and DNA repair
por: Hou, Tianyun, et al.
Publicado: (2020)

The sub-cellular localization of Sulfolobus DNA replication
por: Gristwood, Tamzin, et al.
Publicado: (2012)

Inhibition of DNA replication initiation by silver nanoclusters
por: Tao, Yu, et al.
Publicado: (2021)

High-resolution analysis of four efficient yeast replication origins reveals new insights into the ORC and putative MCM binding elements
por: Chang, FuJung, et al.
Publicado: (2011)

A novel cell-cycle-regulated interaction of the Bloom syndrome helicase BLM with Mcm6 controls replication-linked processes
por: Shastri, Vivek M, et al.
Publicado: (2021)

Crosslinking of DNA repair and replication proteins to DNA in cells treated with 6-thioguanine and UVA
por: Gueranger, Quentin, et al.
Publicado: (2011)

DnaB helicase dynamics in bacterial DNA replication resolved by single-molecule studies
por: Spinks, Richard R, et al.
Publicado: (2021)

Phosphorylated SIRT1 associates with replication origins to prevent excess replication initiation and preserve genomic stability
por: Utani, Koichi, et al.
Publicado: (2017)

Stabilization of G-quadruplex DNA structures in Schizosaccharomyces pombe causes single-strand DNA lesions and impedes DNA replication
por: Obi, Ikenna, et al.
Publicado: (2020)

SIRT6 interacts with TRF2 and promotes its degradation in response to DNA damage
por: Rizzo, Angela, et al.
Publicado: (2017)

SIRT1 regulates DNA damage signaling through the PP4 phosphatase complex
por: Rasti, George, et al.
Publicado: (2023)

A role for chromatin remodellers in replication of damaged DNA
por: Niimi, Atsuko, et al.
Publicado: (2012)

Replication studies of carboxymethylated DNA lesions in human cells
por: Wu, Jun, et al.
Publicado: (2017)

Replication factors transiently associate with mtDNA at the mitochondrial inner membrane to facilitate replication
por: Rajala, Nina, et al.
Publicado: (2014)

Budding yeast Rap1, but not telomeric DNA, is inhibitory for multiple stages of DNA replication in vitro
por: Douglas, Max E, et al.
Publicado: (2021)

SV40 T antigen interactions with ssDNA and replication protein A: a regulatory role of T antigen monomers in lagging strand DNA replication
por: Onwubiko, Nichodemus O, et al.
Publicado: (2020)

The deacetylase SIRT6 promotes the repair of UV-induced DNA damage by targeting DDB2
por: Geng, Anke, et al.
Publicado: (2020)

BRG1 co-localizes with DNA replication factors and is required for efficient replication fork progression
por: Cohen, Stephanie M., et al.
Publicado: (2010)

Bacteriophage SPP1 DNA replication strategies promote viral and disable host replication in vitro
por: Seco, Elena M., et al.
Publicado: (2013)

An intact Mcm10 coiled-coil interaction surface is important for origin melting, helicase assembly and the recruitment of Pol-α to Mcm2–7
por: Perez-Arnaiz, Patricia, et al.
Publicado: (2017)

Two forms of ribosomal protein L2 of Escherichia coli that inhibit DnaA in DNA replication
por: Chodavarapu, Sundari, et al.
Publicado: (2011)

Highly organized DnaA–oriC complexes recruit the single-stranded DNA for replication initiation
por: Ozaki, Shogo, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_2hofa4dgdcumib9nte33b1gij2