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Lysosomal basification and decreased autophagic flux in oxidatively stressed trabecular meshwork cells: Implications for glaucoma pathogenesis

Increasing evidence suggests oxidative damage as a key factor contributing to the failure of the conventional outflow pathway tissue to maintain appropriate levels of intraocular pressure, and thus increase the risk for developing glaucoma, a late-onset disease which is the second leading cause of p...

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Detalles Bibliográficos
Autores principales: Porter, Kristine, Nallathambi, Jeyabalan, Lin, Yizhi, Liton, Paloma B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627672/
https://www.ncbi.nlm.nih.gov/pubmed/23360789
http://dx.doi.org/10.4161/auto.23568