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Purulent bullous epidermal necrolysis: A potential new clinical pattern of drug eruption

Drug eruption is a major problem of adverse drug reactions and may present as variform clinical manifestations. Toxic epidermal necrolysis (TEN) and acute generalized exanthematous pustulosis (AGEP) are relatively rare severe drug eruptions. It has rarely been reported that AGEP overlaps or mimics T...

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Detalles Bibliográficos
Autores principales: LIU, LUN-FEI, YAN, JIAN-LIANG, WANG, JIAN-YOU, CHEN, JI-SU, CAI, SUI-QING, LAO, LI-MIN, ZHENG, MIN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627688/
https://www.ncbi.nlm.nih.gov/pubmed/23596470
http://dx.doi.org/10.3892/etm.2013.944
Descripción
Sumario:Drug eruption is a major problem of adverse drug reactions and may present as variform clinical manifestations. Toxic epidermal necrolysis (TEN) and acute generalized exanthematous pustulosis (AGEP) are relatively rare severe drug eruptions. It has rarely been reported that AGEP overlaps or mimics TEN, while no purulent bullous epidermal necrolysis has been reported. The present study reports a rare case of an adult female patient with the clinical manifestations of purulent bulla and epidermal necrolysis caused by drug ingestion. The case is discussed to reveal whether a new clinical pattern of drug eruption has been identified.